Twelvetrees Lab
Twelvetrees Lab
 


Welcome to the Twelvetrees Lab

The Twelvetrees Lab is a newly established research group at the University of Sheffield, based in the Sheffield Institute for Translational Neuroscience. We are fascinated by how the microtubule cytoskeleton and its motor proteins build and maintain neurons. We aim to understand the molecular mechanisms of this process and create new avenues for translational research. 

 
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Research

 

Explore our research through publications, current projects or our experimental approaches.

 

Lab life

 

Get to know us! Learn about the lab and our location, meet the team or read out latest news on the lab blog.

 

Research Images

 
EB3 comets falling in a dendritic tree.

EB3 comets falling in a dendritic tree.

Individual kinesin molecules walking along immobilised microtubules in vitro.

Individual kinesin molecules walking along immobilised microtubules in vitro.

Dynein-GFP oscillating between developing neurites imaged over 14 hours.

Dynein-GFP oscillating between developing neurites imaged over 14 hours.

Dynein-GFP (cyan) accumulating in the distal axons labelled with for tau (orange).

Dynein-GFP (cyan) accumulating in the distal axons labelled with for tau (orange).

 
A day for ice cream treats in the sunshine 🍦☀️
Snowdrop season
Managed to get a bargain copy of a classic for the lab 🧫 🔬
Trouble shooting a new protocol today #realtimescience
Trying not to feel judged by the instructions for our new pH meter... #doomed #werealldoomed
It’s gel time at the bench! Ashleigh’s cracking on with her final year project :)
It was a big week for looking at small things at the bench! Very impressed by what the Oxford Nanoimager can do. Big thanks for the team behind a great demo of a lovely scope 👍
Guess the conversation from the whiteboard scribbles...
The last few days in Sheffield have been glorious - the meadow behind SITraN has grown two feet in two weeks! #allthegreen #may
The SITraN green roof getting some tlc today; there’s usually a view beyond but we’ve been stuck in this weather for days...